Paget's Disease
Paget’s disease of the nipple, also known as Paget’s disease of the breast, is a rare type of breast cancer.
It produces eczema-like symptoms, appearing as an itchy, red rash on the nipple that can extend to the darker area of surrounding skin (the areola). 90% of women who have it have an underlying breast cancer. The underlying breast cancer may be an invasive breast cancer or ductal carcinoma in situ (DCIS). In DCIS, the cancer cells are completely contained within the milk ducts. In invasive breast cancer, the cancer starts in the ducts or lobes of the breast, and spreads into surrounding breast tissue.
Paget’s disease affects about 1-2 out of every 100 women with breast cancer (1-2%). It's most common in women in their 50s, but can occur at a younger or older age. It can affect men, but this is extremely rare.
Paget's disease usually affects the skin of one nipple, which may be red, dry, sore or scaly. Other possible symptoms include itchiness or a burning sensation, bleeding or discharge from the nipple, which may be streaked with blood.
http://www.patient.co.uk/doctor/pagets-disease-of-breast